Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Specs at a glance
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Laser wavelength
785 nm -
Sample interface
Temperature: probe is non-contact; operating temp: 10 to 50 °C / 50 to 122 °F
Field of application
The union between our Raman analyzers equipped with Rxn-46 bioprocess probe technology and the BioPAT® Spectro platform by Sartorius offers the market an ideal interface to high-throughput development through single-use commercial manufacturing. Our Raman bioprocessing probe technology has been adapted to fit Sartorius’s BioPAT® Spectro platform, utilizing the same probe design for Ambr® 15, Ambr® 250, & Biostat STR® bioreactors.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Benefits
Enables faster, easier, and more robust model building via integration with Ambr® 15 and Ambr® 250
Allows high-throughput process development which supports QbD
Provides a more efficient transfer to Biostat STR® for single-use manufacturing
Offers a scale-independent interface from 15 ml in the laboratory to 2000 L in the production suite
Requires no probe cleaning, sterilization, or frequent maintenance due to non-contact sampling
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
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Success stories
Could also interest you
61 documents
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Technical Information (TI)
Rxn-46 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-46 probe
EN 29/10/202513/12/202411/01/202403/08/202214/09/2021Language:
English
Version:
29/10/2025
File size:
430.4 KB
File name:
TI01634CEN_0525.pdf
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Technical Information (TI)
Raman Rxn-46 calibration and verification kit Technical Information
System design and specifications for the Raman Rxn-46
calibration and verification kitEN 11/01/2024Language:
English
Version:
11/01/2024
File size:
400.4 KB
File name:
TI01765CEN_0123.pdf
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Operating Instruction (BA)
Raman Rxn-46 calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
Raman Rxn-46 calibration and verification kitEN 11/01/2024Language:
English
Version:
11/01/2024
File size:
928.9 KB
File name:
BA02324CEN_0123.pdf
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Operating Instruction (BA)
Rxn-46 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-46 probeEN 29/10/202502/12/202411/01/202403/08/202214/09/2021Language:
English
Version:
29/10/2025
File size:
1.3 MB
File name:
BA02170CEN_0525.pdf
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Short Instruction (KA)
Rxn-46 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-46 probe
EN 02/12/202411/01/202403/08/202214/09/2021Language:
English
Version:
02/12/2024
File size:
529 KB
File name:
KA01550CEN_0424.pdf
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PU (Publication)
Top must-read Biopharma 4.0 articles - Stay informed about the latest research embracing Biopharma 4.0 principles
A list of published technical articles related to Biopharma 4.0
topics with recommendations from Life Science industry experts
at Endress+Hauser.Language:
English
Version:
26/06/2025
File size:
363.4 KB
File name:
PU01611CEN_0125.pdf
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PU (Publication)
Biopharma 4.0 model graphic
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.5 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Bioprocessing infrastructure readiness for online analytical instrumentation integration - Is your upstream operation ready for seamless deployment of an online Raman spectroscopy system?
This self-assessment questionnaire helps pharmaceutical and API
manufacturers evaluate their readiness for implementing online
Raman spectroscopy. A simple scoring system identifies potential
infrastructure, integration, and process monitoring challenges, helping
teams assess deployment complexity and prepare for successful
real-time analytical monitoring.Language:
English
Version:
24/08/2026
File size:
111.2 KB
File name:
PU01649CEN_0126.pdf
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PU (Publication)
Analytical costs, scale-up delays, and optimization potential in upstream bioprocessing - Is your upstream process costing more than you think?
This self-assessment questionnaire helps bioprocessing teams evaluate
analytical costs and delays associated with scaling up from laboratory
development to production. A scoring system helps identify optimization
opportunities and assess the value of real-time monitoring using online
Raman spectroscopy.Language:
English
Version:
24/08/2026
File size:
111.4 KB
File name:
PU01647CEN_0126.pdf
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