Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
785 nm
Temperature: probe is non-contact; operating temp: 10 to 50 °C / 50 to 122 °F
The union between our Raman analyzers equipped with Rxn-46 bioprocess probe technology and the BioPAT® Spectro platform by Sartorius offers the market an ideal interface to high-throughput development through single-use commercial manufacturing. Our Raman bioprocessing probe technology has been adapted to fit Sartorius’s BioPAT® Spectro platform, utilizing the same probe design for Ambr® 15, Ambr® 250, & Biostat STR® bioreactors.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Enables faster, easier, and more robust model building via integration with Ambr® 15 and Ambr® 250
Allows high-throughput process development which supports QbD
Provides a more efficient transfer to Biostat STR® for single-use manufacturing
Offers a scale-independent interface from 15 ml in the laboratory to 2000 L in the production suite
Requires no probe cleaning, sterilization, or frequent maintenance due to non-contact sampling
High-end products
Technical excellence
Simplicity
Standard products
Technical excellence
Simplicity
Specialized products
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
|---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
|
Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
System design and specifications for the Raman Rxn-46
calibration and verification kit
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11/01/2024
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English |
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11/01/2024 |
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400.4 KB |
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File name: |
TI01765CEN_0123.pdf |
System design and specifications for the Raman Rxn-46 probe
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29/10/2025
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13/12/2024
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11/01/2024
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03/08/2022
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14/09/2021
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English |
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29/10/2025 |
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430.4 KB |
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File name: |
TI01634CEN_0525.pdf |
Commissioning, operation, and maintenance details
for the Raman Rxn-46 probe
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29/10/2025
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02/12/2024
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11/01/2024
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03/08/2022
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14/09/2021
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English |
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Version: |
29/10/2025 |
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File size: |
1.3 MB |
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File name: |
BA02170CEN_0525.pdf |
Commissioning, operation, and maintenance details for the
Raman Rxn-46 calibration and verification kit
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11/01/2024
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Language: |
English |
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Version: |
11/01/2024 |
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File size: |
928.9 KB |
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File name: |
BA02324CEN_0123.pdf |
Quick start guide for the Raman Rxn-46 probe
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02/12/2024
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11/01/2024
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03/08/2022
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14/09/2021
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Language: |
English |
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Version: |
02/12/2024 |
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File size: |
529 KB |
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File name: |
KA01550CEN_0424.pdf |
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).
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Language: |
English |
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Version: |
22/05/2025 |
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File size: |
481.6 KB |
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File name: |
PU01614CEN_0125.pdf |
A list of published technical articles related to Biopharma 4.0
topics with recommendations from Life Science industry experts
at Endress+Hauser.
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Language: |
English |
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Version: |
26/06/2025 |
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File size: |
363.4 KB |
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File name: |
PU01611CEN_0125.pdf |
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム(Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム)や水質分
析センサ技術(Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E)などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。
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Language: |
Japanese |
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Version: |
04/10/2024 |
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File size: |
2.5 MB |
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File name: |
PU01585CJA_0124_Graphic_EH biopharma trust.pdf |
This self-assessment questionnaire helps pharmaceutical and API
manufacturers evaluate their readiness for implementing online
Raman spectroscopy. A simple scoring system identifies potential
infrastructure, integration, and process monitoring challenges, helping
teams assess deployment complexity and prepare for successful
real-time analytical monitoring.
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Language: |
English |
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Version: |
24/08/2026 |
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File size: |
111.2 KB |
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File name: |
PU01649CEN_0126.pdf |
This self-assessment questionnaire helps bioprocessing teams evaluate
analytical costs and delays associated with scaling up from laboratory
development to production. A scoring system helps identify optimization
opportunities and assess the value of real-time monitoring using online
Raman spectroscopy.
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Language: |
English |
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Version: |
24/08/2026 |
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File size: |
111.4 KB |
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File name: |
PU01647CEN_0126.pdf |
この製品リストは、ライフサイエンス業界におけるバイオプロセス
用途向けに、光学分析および液体分析の両方から提供される分析機
器をまとめたものです。含まれる製品には、Raman Rxn2アナライザ
、Raman Rxn4アナライザ、Rxn-10プローブ、バイオマルチオプティ
ックおよびバイオスリーブ、ラマンフローアセンブリ、Rxn-45プロ
ーブ、Rxn-46プローブ、シングルユース向けラマンオプティックシ
ステム、Memosens CPS61E、Memosens COS81E、OUSBT66、Memosens
CPS77E、Memosens CLS82E、OUSAF44、Memosens CPS11E、Memosens
CLS16E、TOCアナライザーCA79、Liquiline変換器プラットフォーム
、およびMemobaseソフトウェアが含まれています。
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Language: |
Japanese |
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Version: |
24/08/2025 |
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File size: |
1.2 MB |
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File name: |
PU01484CJA_0224_Lab-to-Process Control in Life Sciences.pdf |
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).
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Language: |
Czech |
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Version: |
06/09/2024 |
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File size: |
381.4 KB |
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File name: |
PU01584CEN_0124_cz_view.pdf |
This guide explains Raman spectroscopy implementation in
GMP-regulated pharmaceutical and biopharmaceutical
manufacturing, covering qualification, validation, data
integrity, supplier and user responsibilities, and
risk-based compliance approaches for process analytical
technology applications.
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Language: |
English |
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Version: |
07/08/2026 |
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File size: |
7.1 MB |
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File name: |
PU01644CEN_0126.pdf |
A guide to our Raman spectroscopy application notes for the
Life Science industry (featuring the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe,
Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single
use optic system / SUB, immersion optic, non-contact optic).
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Language: |
English |
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Version: |
19/04/2022 |
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File size: |
1.1 MB |
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File name: |
PU01447CEN_0222.pdf |
A Q&A about how our Raman spectroscopy analyzer systems
(including the Raman Rxn2 analyzer, Raman Rxn4 analyzer,
and Rxn-46 probe), powered by Kaiser Raman technology, integrates
with the Sartorius BioPAT Spectro platform (Ambr and biostat STR) for
high throughput and single use (SUB) bioprocessing in the
biopharmaceutical life science industry.
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Language: |
English |
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Version: |
08/12/2021 |
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File size: |
943.7 KB |
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File name: |
PU01446CEN_0121.pdf |
この技術文書では、ライフサイエンス産業におけるバイオプロセス
の競争優位性としての拡張性の重要性と、Endress+Hauserの拡張性
のあるラマンシステム(Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45
、Rxn-46、バイオマルチオプティックおよびスリーブ、フローフィ
ル、フローベンチ、シングルユース用Ramanオプティックシステム)
、水質分析センサ技術、および水質分析製品ラインナップ
(LiquilineCM44P、CM442、OUSAF44、OUSBT66、Memosens CPS61E、
CLS82E、COS81E、CLS82E)について考察しています。
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Language: |
Japanese |
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Version: |
04/10/2024 |
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File size: |
1.2 MB |
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File name: |
PU01584CJA_0124_Scalability in biopharma development.pdf |
Ein Leitfaden zu unseren Anwendungshinweisen zur
Raman-Spektroskopie für die Life-Science-Industrie
(Raman Rxn2-Analysator, Raman Rxn4-Analysator,
Rxn-10-Sonde, Rxn-20-Sonde, Rxn-45-Sonde,
Rxn-46-Sonde und Zubehör für Sondenoptiken
(blO-Optic, Raman- Single Use-Optiksystem
/ SUB, Immersionsoptik, berührungslose Optik)
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Language: |
German |
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Version: |
24/09/2025 |
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File size: |
1.4 MB |
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File name: |
PU01447CDE_0222_Raman-Anwendungsleitfaden_LSI_web.pdf |
Expanded version of a graphic illustrating the core elements of
Biopharma 4.0 including product lifecycle stages, role of
PAT/QbD, and 12 key advanced technologies for scientists and
process engineers in the Life Sciences, applicable to Raman
spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10,
Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use, and Raman calibration
& verification kits).
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Language: |
English |
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Version: |
22/05/2025 |
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File size: |
29.1 MB |
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File name: |
PU01613CEN_0125.pdf |
This self-assessment questionnaire helps API synthesis teams in the
Life Sciences industry identify analytical blind spots and assess the
value of real-time inline Raman spectroscopy for monitoring API
crystallization processes.
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Language: |
English |
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Version: |
24/08/2026 |
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File size: |
110.8 KB |
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File name: |
PU01646CEN_0126.pdf |
This self-assessment questionnaire helps cell culture and upstream
bioprocessing teams identify analytical blind spots, contamination
risks from manual sampling, and opportunities to improve process
control through real-time monitoring. A simple scoring system
highlights where online Raman spectroscopy may help improve data
quality, reduce risk, and support faster process decisions.
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Language: |
English |
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Version: |
24/08/2026 |
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File size: |
111 KB |
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File name: |
PU01648CEN_0126.pdf |